uspto-grants-1999_11 · 10.6084/m9.figshare.5104873.v1 · US05981507
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IDENTITY
结构与身份
- 标准SMILES
- NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)n1
- InChIKey
- SDWIOXKHTFOULX-AFCXAGJDSA-N
- 分子式
- C8H13N4O8P
- 平均分子量
- 324.18 g/mol
- 单同位素质量
- 324.04710038
COMPUTED
结构计算性质
- XLogP
- -3.5
- 极性表面积
- 190 Ų
- 氢键供体
- 5
- 氢键受体
- 10
- 可旋转键
- 5
- 重原子
- 21
- 形式电荷
- 0
- 复杂度
- 446
PHARMACOLOGY
药理信息
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
ALIASES
名称与别名
Ribavirin monophosphate40925-28-8Ribavirin-5'-phosphateRibavirin 5'-monophosphateRibavirin 5'-phosphate1-(5-O-Phosphono-beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamideO9FVV27P11CHEBI:45490DTXSID20193928NSC-274937RefChem:930750DTXCID601164191 beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-phosphate(((2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)phosphonic acidVirazole 5'-phosphateICN 38471beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-phosphate1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-phosphono-.beta.-D-ribofuranosyl)-RVPUNII-O9FVV27P11
REACTIONS
参与反应