uspto-grants-1979_05 · 10.6084/m9.figshare.5104873.v1 · US04152435
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IDENTITY
结构与身份
- 标准SMILES
- NNc1nnc(NN)c2ccccc12
- InChIKey
- VQKLRVZQQYVIJW-UHFFFAOYSA-N
- 分子式
- C8H10N6
- 平均分子量
- 190.21 g/mol
- 单同位素质量
- 190.09669434
COMPUTED
结构计算性质
- XLogP
- 0.2
- 极性表面积
- 102 Ų
- 氢键供体
- 4
- 氢键受体
- 6
- 可旋转键
- 2
- 重原子
- 14
- 形式电荷
- 0
- 复杂度
- 167
HAZARDS
危害信息
Other Safety Information
IMAP assessments - 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone: Environment tier I assessment；IMAP assessments - 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone: Human health tier I assessment
PHARMACOLOGY
药理信息
ATC Code
C - Cardiovascular system；C02 - Antihypertensives；C02D - Arteriolar smooth muscle, agents acting on；C02DB - Hydrazinophthalazine derivatives；C02DB01 - Dihydralazine
QC - Cardiovascular system；QC02 - Antihypertensives；QC02D - Arteriolar smooth muscle, agents acting on；QC02DB - Hydrazinophtalazine derivatives；QC02DB01 - Dihydralazine
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
USES
用途与制造
Uses
Use (kg; approx.) in Germany (2009): >500；Consumption (g per capita; approx.) in Germany (2009): 0.00611；Calculated removal (%): 75.1
ALIASES
名称与别名
DIHYDRALAZINE484-23-11,4-DihydrazinophthalazineDihydrallazinDihydrallazineHypopresol1,4-dihydrazinylphthalazineDihydrazinophthalazineDihidralazinaDihydralazinum2,3-Dihydro-1,4-phthalazinedione dihydrazoneC 7441DTXSID00229351,4-Phthalazinedione, 2,3-dihydro-, dihydrazoneNSC-526654PCU411F5L6DTXCID902935NSC526654Dihydrazinophthalazindiidralazina
REACTIONS
参与反应