8-Aminoquinoline 分子结构式
HCID11359

8-Aminoquinoline

quinolin-8-amine

C9H8N2144.17 g/molCAS 578-66-5

IDENTITY

结构与身份

标准SMILES
Nc1cccc2cccnc12
InChIKey
WREVVZMUNPAPOV-UHFFFAOYSA-N
分子式
C9H8N2
平均分子量
144.17 g/mol
单同位素质量
144.06874826

COMPUTED

结构计算性质

已同步
XLogP
1.8
极性表面积
38.9 Ų
氢键供体
1
氢键受体
2
可旋转键
0
重原子
11
形式电荷
0
复杂度
136

PROPERTIES

实验与物化性质

来源:PubChem
Vapor Pressure

0.00055 [mmHg]

Physical Description

Yellow solidified mass or fragments; [Aldrich MSDS]

GHS

GHS分类

来源:PubChem
GHS Classification

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (19.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (11.5%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 52 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Regulatory Information

Chemical: 8-Quinolinamine

8-Aminoquinoline: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary

A skin and strong eye irritant; [Aldrich MSDS] See 5-Aminoquinoline.

Hazard Classes and Categories

Skin Irrit. 2 (100%);Eye Irrit. 2A (100%);STOT SE 3 (19.2%);Muta. 2 (11.5%)

REGULATORY

法规信息

来源:PubChem
Regulatory Information

Chemical: 8-Quinolinamine

8-Aminoquinoline: Does not have an individual approval but may be used under an appropriate group standard

USES

用途与制造

来源:PubChem
General Manufacturing Information

8-Quinolinamine: ACTIVE

ALIASES

名称与别名

共 71 条
8-AMINOQUINOLINE578-66-58-Quinolinamine8-QuinolylamineQuinoline, 8-amino-U34EAV21TGWR 6920NSC-7933DTXSID4060369NC-066WR-6920RefChem:547592DTXCID8042262WR006026WR-006026209-427-9N,N-diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediaminequinolin-8-amineMFCD00006809AS-232

REACTIONS

参与反应

172
HRID 11854 反应方程式

uspto-grants-2006_08 · 10.6084/m9.figshare.5104873.v1 · US07098215B2

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HRID 33548 反应方程式

uspto-grants-2008_09 · 10.6084/m9.figshare.5104873.v1 · US07429608B2

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HRID 41319 反应方程式

uspto-grants-2013_09 · 10.6084/m9.figshare.5104873.v1 · US08530593B2

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HRID 41323 反应方程式

uspto-grants-2013_09 · 10.6084/m9.figshare.5104873.v1 · US08530593B2

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HRID 52555 反应方程式

uspto-grants-1997_04 · 10.6084/m9.figshare.5104873.v1 · US05616586

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HRID 91144 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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HRID 105134 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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HRID 120818 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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