Acetohydrazide 分子结构式
HCID14039

Acetohydrazide

C2H6N2O74.08 g/molCAS 1068-57-1

IDENTITY

结构与身份

标准SMILES
CC(=O)NN
InChIKey
OFLXLNCGODUUOT-UHFFFAOYSA-N
分子式
C2H6N2O
平均分子量
74.08 g/mol
单同位素质量
74.04801282

COMPUTED

结构计算性质

已同步
XLogP
-1.6
极性表面积
55.1 Ų
氢键供体
2
氢键受体
2
可旋转键
0
重原子
5
形式电荷
0
复杂度
42

GHS

GHS分类

来源:PubChem
GHS Classification

Danger

H301 (54.7%): Toxic if swallowed [Danger Acute toxicity, oral];H302 (41.9%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (67.4%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (67.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H331 (32.6%): Toxic if inhaled [Danger Acute toxicity, inhalation];H341 (54.7%): Suspected of causing genetic defects [Warning Germ cell mutagenicity];H351 (55.8%): Suspected of causing cancer [Warning Carcinogenicity];H400 (32.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410 (32.6%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard];H411 (32.6%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P203, P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P318, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 86 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Regulatory Information

Status: Active Update: 05-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23789

Acetohydrazide: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories

Acute Tox. 3 (54.7%);Acute Tox. 4 (41.9%);Skin Irrit. 2 (67.4%);Eye Irrit. 2 (67.4%);Acute Tox. 3 (32.6%);Muta. 2 (54.7%);Carc. 2 (55.8%);Aquatic Acute 1 (32.6%);Aquatic Chronic 2 (32.6%)

REGULATORY

法规信息

来源:PubChem
Regulatory Information

Status: Active Update: 05-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23789

Acetohydrazide: Does not have an individual approval but may be used under an appropriate group standard

PHARMACOLOGY

药理信息

来源:PubChem
MeSH Pharmacological Classification

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Tissue Locations

Kidney;Liver

USES

用途与制造

来源:PubChem
General Manufacturing Information

Acetic acid, hydrazide: ACTIVE

ALIASES

名称与别名

共 75 条
AcethydrazideAcetohydrazide1068-57-1AcetylhydrazineAcetic hydrazideAcetyl hydrazideMonoacetylhydrazineEthanehydrazonic acidN-AcetylhydrazineHydrazine, acetyl-ENT-61241acethydrazineSK0DPC9098NSC-2271NSC-53155CHEBI:2422acetylhydrazideRefChem:552505213-948-7Acetic acid hydrazide

REACTIONS

参与反应

346
HRID 25074 反应方程式

uspto-grants-2005_02 · 10.6084/m9.figshare.5104873.v1 · US06858605B2

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HRID 28353 反应方程式

uspto-grants-2008_09 · 10.6084/m9.figshare.5104873.v1 · US07419963B2

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HRID 44516 反应方程式

uspto-grants-2013_09 · 10.6084/m9.figshare.5104873.v1 · US08541411B2

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HRID 60055 反应方程式

uspto-grants-2016_09 · 10.6084/m9.figshare.5104873.v1 · US09440963B2

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HRID 87930 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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HRID 99772 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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HRID 107031 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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HRID 115950 反应方程式

Training data from https://doi.org/10.1039/C8SC04228D (2/10) · 10.1039/C8SC04228D

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