uspto-grants-2007_12 · 10.6084/m9.figshare.5104873.v1 · US07304182B2
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IDENTITY
结构与身份
- 标准SMILES
- O=C([O-])c1ccc(O)cc1.[Na+]
- InChIKey
- ZLVSYODPTJZFMK-UHFFFAOYSA-M
- 分子式
- C7H5NaO3
- 平均分子量
- 160.1 g/mol
- 单同位素质量
- 160.0136383
COMPUTED
结构计算性质
- 极性表面积
- 60.4 Ų
- 氢键供体
- 1
- 氢键受体
- 3
- 可旋转键
- 1
- 重原子
- 11
- 形式电荷
- 0
- 复杂度
- 130
GHS
GHS分类
GHS Classification
This chemical does not meet GHS hazard criteria for 3.5% (3 of 86) of reports.
Warning
H315 (96.5%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (96.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (95.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 86 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 3 of 86 reports by companies.；There are 5 notifications provided by 83 of 86 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
HAZARDS
危害信息
Regulatory Information
Benzoic acid, 4-hydroxy-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and Categories
Skin Irrit. 2 (96.5%)；Eye Irrit. 2 (96.5%)；STOT SE 3 (95.3%)
TOXICITY
毒理信息
Toxicity Summary
The CIR Expert Panel concluded that the following 20 parabens are safe in cosmetics in the present practices of use and concentration described in the safety assessment when the sum of the combined concentration of parabens in any given formulation does not exceed 0.8 %...Sodium Paraben...
Safe for use in cosmetics, with qualifications
REGULATORY
法规信息
Regulatory Information
Benzoic acid, 4-hydroxy-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
USES
用途与制造
Uses
CIR ingredient: Sodium Paraben
Use Classification
Cosmetics -> Preservative
General Manufacturing Information
Benzoic acid, 4-hydroxy-, sodium salt (1:1): ACTIVE
ALIASES
名称与别名
Sodium 4-hydroxybenzoateSodium p-hydroxybenzoate4-Hydroxybenzoic acid sodium saltsodium parabenBenzoic acid, 4-hydroxy-, monosodium saltp-Hydroxybenzoic acid sodium saltMonosodium p-hydroxybenzoateMonosodium 4-hydroxybenzoateBenzoic acid, 4-hydroxy-, sodium salt (1:1)EINECS 204-051-1p-hydroxybenzoic acid monosodium saltV6102T509BDTXSID3059426BENZOIC ACID, p-HYDROXY-, SODIUM SALTCHEBI:113449SODIUM 4-HYDROXYBENZOIC ACIDBENZOIC ACID, P-HYDROXY-, MONOSODIUM SALTRefChem:887100SODIUM PARABEN [INCI]DTXCID5033337
REACTIONS
