2,6-Dichloropyridine 分子结构式
HCID16989

2,6-Dichloropyridine

C5H3Cl2N147.99 g/molCAS 2402-78-0

IDENTITY

结构与身份

标准SMILES
Clc1cccc(Cl)n1
InChIKey
FILKGCRCWDMBKA-UHFFFAOYSA-N
分子式
C5H3Cl2N
平均分子量
147.99 g/mol
单同位素质量
146.9642545

COMPUTED

结构计算性质

已同步
XLogP
2.2
极性表面积
12.9 Ų
氢键供体
0
氢键受体
1
可旋转键
0
重原子
8
形式电荷
0
复杂度
68

PROPERTIES

实验与物化性质

来源:PubChem
Physical Description

Wet Solid

White crystalline solid; [Alfa Aesar MSDS]

GHS

GHS分类

来源:PubChem
GHS Classification

Danger

H301 (96.6%): Toxic if swallowed [Danger Acute toxicity, oral];H315 (15.5%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (15.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 58 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Regulatory Information

Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary

Causes somnolence and fatty liver degeneration in intraperitoneal lethal-dose studies of mice; [RTECS] An irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Pyridine.

Hazard Classes and Categories

Acute Tox. 3 (96.6%);Skin Irrit. 2 (15.5%);Eye Irrit. 2A (15.5%);STOT SE 3 (12.1%)

TOXICITY

毒理信息

来源:PubChem
Adverse Effects

Neurotoxin - Other CNS neurotoxin;Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

REGULATORY

法规信息

来源:PubChem
Regulatory Information

Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard

USES

用途与制造

来源:PubChem
U.S. Production

2023: 53,953 lb;2022: 186,928 lb;2021: 226,252 lb;2020: 232,841 lb

Industry Uses

Intermediate

General Manufacturing Information

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing

Pyridine, 2,6-dichloro-: ACTIVE

ALIASES

名称与别名

共 47 条
2,6-DICHLOROPYRIDINE2402-78-0Pyridine, 2,6-dichloro-DTXSID2051895WM26PC2SBWNSC-76606DTXCID0030457RefChem:83196219-282-3MFCD000062442,6-Dichloro-pyridine2,6-Dichloropyridine, 98%CCRIS 1727EINECS 219-282-3NSC 76606BRN 0108664NSC766062,6-dichlorpyridine2.6-dichloropyridineUNII-WM26PC2SBW

REACTIONS

参与反应

156
HRID 423 反应方程式

750 AstraZeneca ELN dataset

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HRID 638 反应方程式

750 AstraZeneca ELN dataset

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HRID 3295 反应方程式

uspto-grants-1998_03 · 10.6084/m9.figshare.5104873.v1 · US05733912

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HRID 50875 反应方程式

uspto-grants-2004_03 · 10.6084/m9.figshare.5104873.v1 · US06713482B2

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HRID 55118 反应方程式

uspto-grants-1997_04 · 10.6084/m9.figshare.5104873.v1 · US05624942

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HRID 55120 反应方程式

uspto-grants-1997_04 · 10.6084/m9.figshare.5104873.v1 · US05624942

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HRID 71074 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08822708B2

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HRID 75926 反应方程式

uspto-grants-2014_09 · 10.6084/m9.figshare.5104873.v1 · US08835465B2

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