750 AstraZeneca ELN dataset
查看IDENTITY
结构与身份
- 标准SMILES
- Clc1cccc(Cl)n1
- InChIKey
- FILKGCRCWDMBKA-UHFFFAOYSA-N
- 分子式
- C5H3Cl2N
- 平均分子量
- 147.99 g/mol
- 单同位素质量
- 146.9642545
COMPUTED
结构计算性质
- XLogP
- 2.2
- 极性表面积
- 12.9 Ų
- 氢键供体
- 0
- 氢键受体
- 1
- 可旋转键
- 0
- 重原子
- 8
- 形式电荷
- 0
- 复杂度
- 68
PROPERTIES
实验与物化性质
Physical Description
Wet Solid
White crystalline solid; [Alfa Aesar MSDS]
GHS
GHS分类
GHS Classification
Danger
H301 (96.6%): Toxic if swallowed [Danger Acute toxicity, oral];H315 (15.5%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (15.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 58 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
HAZARDS
危害信息
Regulatory Information
Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Causes somnolence and fatty liver degeneration in intraperitoneal lethal-dose studies of mice; [RTECS] An irritant; Toxic by ingestion; [Alfa Aesar MSDS] See Pyridine.
Hazard Classes and Categories
Acute Tox. 3 (96.6%);Skin Irrit. 2 (15.5%);Eye Irrit. 2A (15.5%);STOT SE 3 (12.1%)
TOXICITY
毒理信息
Adverse Effects
Neurotoxin - Other CNS neurotoxin;Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
REGULATORY
法规信息
Regulatory Information
Pyridine, 2,6-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2,6-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Pyridine, 2,6-dichloro-: Does not have an individual approval but may be used under an appropriate group standard
USES
用途与制造
U.S. Production
2023: 53,953 lb;2022: 186,928 lb;2021: 226,252 lb;2020: 232,841 lb
Industry Uses
Intermediate
General Manufacturing Information
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Pyridine, 2,6-dichloro-: ACTIVE
ALIASES
名称与别名
REACTIONS
参与反应
750 AstraZeneca ELN dataset
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