Ropivacaine Hydrochloride 分子结构式
HCID175804

Ropivacaine Hydrochloride

(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride

C17H27ClN2O310.9 g/molCAS 98717-15-8

IDENTITY

结构与身份

标准SMILES
CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl
InChIKey
NDNSIBYYUOEUSV-RSAXXLAASA-N
分子式
C17H27ClN2O
平均分子量
310.9 g/mol
单同位素质量
310.1811912

COMPUTED

结构计算性质

已同步
极性表面积
32.3 Ų
氢键供体
2
氢键受体
2
可旋转键
4
重原子
21
形式电荷
0
复杂度
308

GHS

GHS分类

来源:PubChem
GHS Classification

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

PHARMACOLOGY

药理信息

来源:PubChem
FDA Pharmacological Classification

ROPIVACAINE HYDROCHLORIDE

Amide Local Anesthetic [EPC]; Amides [CS]; Local Anesthesia [PE]

MeSH Pharmacological Classification

Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.

ALIASES

名称与别名

共 72 条
Ropivacaine hydrochlorideROPIVACAINE HCl98717-15-8Ropivacaine monohydrochlorideDTXSID204837935504LBE2TDTXCID2028353ROPIVACAINE HYDROCHLORIDE [MI]ROPIVACAINE HYDROCHLORIDE [MART.]ROPIVACAINE HYDROCHLORIDE ANHYDROUSROPIVACAINE HYDROCHLORIDE [WHO-DD]2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride, (S)-(S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE(S)-(-)-1-PROPYLPIPERIDINE-2-CARBOXYLIC ACID (2,6-DIMETHYLPHENYL)AMIDE HYDROCHLORIDEROPIVACAINE HYDROCHLORIDE (MART.)ROPIVACAINE HYDROCHLORIDE [VANDF]ROPIVACAINE HYDROCHLORIDE [ORANGE BOOK]ROPIVACAINE HYDROCHLORIDE (USP MONOGRAPH)ROPIVACAINE HYDROCHLORIDE [USP MONOGRAPH]ROPIVACAINE HYDROCHLORIDE MONOHYDRATE [MI]

REACTIONS

参与反应

1
HRID 2273580 反应方程式

uspto-grants-2015_09 · 10.6084/m9.figshare.5104873.v1 · US09125814B2

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