Cytosine

-1.73

8.0 mg/mL

>16.7 [ug/mL] (The mean of the results at pH 7.4)

> 300 °C

0.00109 [mmHg]

Monohydrate: Lustrous solid; [Merck Index] White powder; [Alfa Aesar MSDS]

Solid

Positive

2.5

2.7

Agilent XCT

Electrospray ionization

formic acid (5.3nM)

118.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4044456]；117.3 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID4044456]

117.5 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]；122.8 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

121.58 Ų [M+H]+ [CCS Type: DT; Method: stepped-field]

117.4 Ų [M+H]+；122.6 Ų [M+H]+

This chemical does not meet GHS hazard criteria for 13.6% (8 of 59) of reports.

Warning

H315 (86.4%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (86.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (84.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 59 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 8 of 59 reports by companies.；There are 8 notifications provided by 51 of 59 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: 2(1H)-Pyrimidinone, 4-amino-

Status: Active Update: 26-06-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/6166

2(1H)-Pyrimidinone, 4-amino-: Does not have an individual approval but may be used under an appropriate group standard

IMAP assessments - 2(1H)-Pyrimidinone, 4-amino-: Environment tier I assessment

Causes somnolence and changes in motor activity in intraperitoneal lethal-dose studies of mice; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS]

Skin Irrit. 2 (86.4%)；Eye Irrit. 2A (86.4%)；STOT SE 3 (84.7%)

Chemical: 2(1H)-Pyrimidinone, 4-amino-

Status: Active Update: 26-06-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/6166

2(1H)-Pyrimidinone, 4-amino-: Does not have an individual approval but may be used under an appropriate group standard

Blood；Epidermis；Fibroblasts；Intestine；Neuron；Placenta；Prostate；Skeletal Muscle；Spleen；Testis

Extracellular

Component of nucleic acids found throughout nature; [Merck Index] Used in biochemical research; [Alfa Aesar MSDS]

2(1H)-Pyrimidinone, 6-amino-: ACTIVE