HCID2309

Befunolol

1-[7-[2-hydroxy-3-(propan-2-ylamino)propoxy]-1-benzofuran-2-yl]ethanone

C16H21NO4291.34 g/molCAS 39552-01-7

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IDENTITY

结构与身份

标准SMILES: CC(=O)c1cc2cccc(OCC(O)CNC(C)C)c2o1
InChIKey: ZPQPDBIHYCBNIG-UHFFFAOYSA-N
分子式: C16H21NO4
平均分子量: 291.34 g/mol
单同位素质量: 291.14705815

COMPUTED

结构计算性质

已同步

XLogP: 2
极性表面积: 71.7 Å²
氢键供体: 2
氢键受体: 5
可旋转键: 7
重原子: 21
形式电荷: 0
复杂度: 347

PROPERTIES

实验与物化性质

来源：PubChem

Melting Point

115

PHARMACOLOGY

药理信息

来源：PubChem

ATC Code

S - Sensory organs；S01 - Ophthalmologicals；S01E - Antiglaucoma preparations and miotics；S01ED - Beta blocking agents；S01ED06 - Befunolol

QS - Sensory organs；QS01 - Ophthalmologicals；QS01E - Antiglaucoma preparations and miotics；QS01ED - Beta blocking agents；QS01ED06 - Befunolol

MeSH Pharmacological Classification

Drugs that selectively bind to and activate beta-adrenergic receptors.

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

ALIASES

名称与别名

共 49 条

Befunolol39552-01-7Befunololum7-(2-Hydroxy-3-(isopropylamino)propoxy)-2-benzofuranyl methyl ketone418546MT3A2-Acetyl-7-(2-hyroxy-3-isopropylaminopropoxy)benzofuran1-(7-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)ethanone1-[7-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]ethanone1-(7-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)ethanone hydrochloride2-acetyl-7-(2-hydroxy-3-isopropylamino)propoxybenzofuranbefunololoRefChem:116875S01ED06Befunolol [INN]()-BefunololBefunolol (INN)(+/-)-Befunolol( inverted exclamation markA)-Befunolol2-acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran1-[7-[2-hydroxy-3-(propan-2-ylamino)propoxy]-1-benzofuran-2-yl]ethanone

REACTIONS

参与反应

1 条

uspto-grants-1977_11 · 10.6084/m9.figshare.5104873.v1 · US04056626

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