结构:[K+].[O-][I+2]([O-])[O-]
HCID23665710

Potassium Iodate

IKO3214.001 g/molCAS 7758-05-6

IDENTITY

结构与身份

标准 SMILES
[K+].[O-][I+2]([O-])[O-]
InChIKey
JLKDVMWYMMLWTI-UHFFFAOYSA-M
分子式
IKO3
平均分子量
214.001 g/mol
单同位素质量
213.85292

COMPUTED

结构计算性质

已同步
极性表面积
57.2 Ų
氢键供体
0
氢键受体
3
可旋转键
0
重原子
5
形式电荷
0
复杂度
49

PROPERTIES

实验与物化性质

来源:PubChem
Odor

Odorless

Density

3.98

3.89 @25 °C

Color/Form

White crystals or crystalline powder

Colorless monoclinic crystals

Solubility

4.74 g/100 cc water @ 0 °C; 32.3 g/100 cc @ 100 °C; insol in alc, nitric acid; sol in potassium iodide

Sol in dil sulfuric acid

9.16 g/100 g H20 at 25 °C

Decomposition

When heated to decomposition it emits very toxic fumes.

Melting Point

560 °C

560 °C

Physical Description

White crystals or crystalline powder. [HSDB]

Other Experimental Properties

Partial decomp @ 560 °C

DECOMP @ GREATER THAN 100 °C

GHS

GHS 分类

来源:PubChem
GHS Classification

Danger

H272 (85.3%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids];H302 (58.2%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (59.6%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (66.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (59.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P220, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 443 reports by companies from 25 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

HAZARDS

危害信息

来源:PubChem
Regulatory Information

Chemical: Iodic acid (HIO3), potassium salt

Status: Active Update: 01-07-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13616

Iodic acid, potassium salt: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information

IMAP assessments - Iodic acid and selected salts: Human health tier II assessment

Fire Potential

...DANGEROUS BECAUSE THEY ARE STRONG OXIDIZERS. IN CONTACT WITH FLAMMABLE OR EVEN COMBUSTIBLE MATERIALS THEY CAN START FIRES. /IODATES/

Hazards Summary

Causes gastrointestinal tract, liver, and kidney injury in high-dose animal experiments; [HSDB]

FDA Requirements

Substance added directly to human food affirmed as generally recognized as safe (GRAS).

Special Reports

REVIEW OF THE HEALTH ASPECTS OF POTASSIUM IODIDE, POTASSIUM IODATE, & CALCIUM IODATE AS FOOD INGREDIENTS.[LIFE SCIENCES RESEARCH OFFICE/FEDERATION OF AMERICAN SOCIETIES FOR EXPTL BIOLOGY; EVALUATION OF THE HEALTH ASPECTS OF POTASSIUM IODIDE, POTASSIUM IODATE, & CALCIUM IODATE AS FOOD INGREDIENTS; USNTIS PB REPORT PB-254 533: 22 PP (1975)]

Hazard Classes and Categories

Ox. Sol. 2 (85.3%);Acute Tox. 4 (58.2%);Skin Irrit. 2 (59.6%);Eye Irrit. 2 (66.8%);STOT SE 3 (59.4%)

Acute toxicity (ingestion) - category 4;Specific target organ toxicity (single exposure) - category 2

Acute toxicity (Oral) - Category 4

Hazardous Reactivities and Incompatibilities

CAN REACT VIGOROUSLY WITH REDUCING MATERIALS

Potentially explosive reaction with charcoal + ozone; metals; arsenic; carbon; phosphorus; sulfur; alkali metal hydrides; alkaline earth metal hydrides; antimony sulfide; arsenic sulfide; copper sulfide; tin sulfide; metal cyanides; metal thiocyanates; manganese dioxide. Violent reaction with organic matter.

SAFETY

安全与防护

来源:PubChem
Disposal Methods

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Protective Action Criteria (PAC)

3.6 [mg/m3]

40 [mg/m3]

240 [mg/m3]

TOXICITY

毒理信息

来源:PubChem
Adverse Effects

Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

Human Toxicity Excerpts

NO HUMAN INGESTION OF IODATE SALTS CAN BE CITED. /IODATE SALTS/

Non-Human Toxicity Excerpts

...IN FASTING DOG...0.2-0.25 G/KG...USUALLY CAUSE/S/ EMESIS, BUT IF THIS IS PREVENTED SIGNS OF ANOREXIA AND PROSTRATION PRECEDE DEATH. NECROTIC LESIONS OF THE LIVER, KIDNEYS AND GASTRIC AND INTESTINAL MUCOSA...

POTASSIUM & SODIUM IODATE HAVE ABOUT THE SAME LD50 & PRODUCE DEATH IN ACUTE RENAL FAILURE /IN MICE/...SOMETIMES HEMOGLOBINURIA PRECEDED RENAL SHUTDOWN.

POTASSIUM IODATE INDUCED STERILITY IN COPTA MITE (T PUTRESCENTIAE) WHEN GIVEN IN DIET @ 0.25-1.0% CONCN FOR 1-2 WK. FEMALES WERE MORE SUSCEPTIBLE THAN MALES. EGG FORMATION WAS DETRIMENTALLY AFFECTED.

POTASSIUM IODATE INDUCED DEFORMED SPIRACLES IN PUPAE WHEN FED TO SILKWORM LARVAE @ 100 PPM IODINE.

Non-Human Toxicity Values

LD50 Mouse ip 136 mg/kg

REGULATORY

法规信息

来源:PubChem
Regulatory Information

Chemical: Iodic acid (HIO3), potassium salt

Status: Active Update: 01-07-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13616

Iodic acid, potassium salt: Does not have an individual approval but may be used under an appropriate group standard

FDA Requirements

Substance added directly to human food affirmed as generally recognized as safe (GRAS).

PHARMACOLOGY

药理信息

来源:PubChem
MeSH Pharmacological Classification

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.

USES

用途与制造

来源:PubChem
Uses

Used as a reagent to test for zinc and arsenic, a photographic emulsion, a feed additive, a dietary supplement, and in spectroscopy, infrared transmission, and scintillation; [Hawley] Classification code: Anti-infective agents; antifungal agents; [ChemIDplus]

Photographic Processing [Category: Other];Farming (Feed Additives) [Category: Industry]

MEDICATION (VET)

Medication

Oxidizing agent in volumetric chemical analysis

REAGENT IN MERCURY REDN METHOD OF PYRETHRIN ANALYSIS

Methods of Manufacturing

Prepared by dissolving iodine in a caustic alkali solution and recovering the iodate by filtration.

Prepared by oxidation of iodine to iodic acid, followed by neutralization with an oxide or hydroxide; or by electrolytic oxidation of an iodide solution.

Formulations/Preparations

Grades: ...CP; FCC; Technical

/Available as/ techincal, FCC food grades; 99.9% purity grade; ACS reagent grade

Use Classification

Food Additives -> FLOUR_TREATMENT_AGENT -> JECFA Functional Classes

General Manufacturing Information

Iodic acid (HIO3), potassium salt (1:1): ACTIVE

RECOMMENDED BY WORLD HEALTH ORGANIZATION AS AN ADDITIVE TO TABLE SALT TO PREVENT GOITER /IODATES/.

Iodates are precipitated when solutions of metal salts react with alkali-metal iodates.

Formed when potassium iodide is fused with potassium chlorate, bromate, or perchlorate.

ALIASES

名称与别名

42
POTASSIUM IODATE7758-05-6Iodic acid, potassium saltIodic acid (HIO3), potassium saltI139E44NHLPotassium iodine oxide (KIO3)DTXSID5058480NSC-215201IODIC ACID (HIO3) POTASSIUM SALT (1:1)RefChem:6157DTXCID9032248231-831-9Potassium triodateKaliumjodatpotassium;iodatePotassium iodine oxideMFCD00011406Caswell No. 693AIKO3kalium iodate

REACTIONS

参与反应

32