uspto-grants-1998_03 · 10.6084/m9.figshare.5104873.v1 · US05726306
查看IDENTITY
结构与身份
- 标准SMILES
- CCI
- InChIKey
- HVTICUPFWKNHNG-UHFFFAOYSA-N
- 分子式
- C2H5I
- 平均分子量
- 155.97 g/mol
- 单同位素质量
- 155.9436
COMPUTED
结构计算性质
- XLogP
- 2.1
- 极性表面积
- 0 Ų
- 氢键供体
- 0
- 氢键受体
- 0
- 可旋转键
- 0
- 重原子
- 3
- 形式电荷
- 0
- 复杂度
- 2
PROPERTIES
实验与物化性质
LogP
2.0
Density
Relative density (water = 1): 1.936
1.948 @ 15°C
Solubility
Solubility in water, g/100ml at 20 °C: 0.4
Flash Point
61 °C c.c.
Boiling Point
72 °C
72.4 °C @760 [mm Hg]
Melting Point
-108 °C
-108 °C
Vapor Density
Relative vapor density (air = 1): 5.4 (calculated)
Vapor Pressure
136.0 [mmHg]
Vapor pressure, kPa at 18 °C: 13.3
100 [mm Hg] @18 °C
Physical Description
Gas Vapor; Liquid
Highly refractive liquid with an ethereal odor; Colorless when fresh, turns red on exposure to light and air; [Merck Index]
COLOURLESS LIQUID WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO LIGHT.
Kovats Retention Index
602;607;614;621;601;600;601;602;600.4
616;586;617.6;638.9;591;598;609;621;616.3
881;896.49;899.84;901.65;892;876;892;880
GHS
GHS分类
GHS Classification
Danger
H226 (18.5%): Flammable liquid and vapor [Warning Flammable liquids];H302 (98.5%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (91.5%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (88.5%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (86.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (12.3%): Harmful if inhaled [Warning Acute toxicity, inhalation];H334 (84.6%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory];H335 (90.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (10%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P370+P378, P403, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 130 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
HAZARDS
危害信息
Regulatory Information
Chemical: Ethane, iodo-
Ethane, iodo- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethane, iodo- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 27-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/24183
Iodoethane: Does not have an individual approval but may be used under an appropriate group standard
Fire Hazards
Flammable. Above 61 °C explosive vapour/air mixtures may be formed.
Hazards Summary
Causes lung changes and flaccid paralysis without anesthesia in subcutaneous lethal-dose studies of mice; [RTECS] A skin, eye, and respiratory tract irritant; May have CNS effects (lowering of consciousness); Can be absorbed through skin; [ICSC] An irritant that may cause serious eye injury; May cause skin sensitization; Harmful by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS] See Ethyl chloride and Ethyl bromide,
Chemical Dangers
Decomposes on burning. This produces iodine and hydrogen iodide. Reacts with strong bases and strong oxidants.
Physical Dangers
The vapour is heavier than air.
Hazard Classes and Categories
Flam. Liq. 3 (18.5%);Acute Tox. 4 (98.5%);Skin Irrit. 2 (91.5%);Skin Sens. 1 (88.5%);Eye Irrit. 2 (86.9%);Acute Tox. 4 (12.3%);Resp. Sens. 1 (84.6%);STOT SE 3 (90.8%);Muta. 2 (10%)
SAFETY
安全与防护
Fire Fighting
Use water spray, powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
First Aid Measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Safe Storage
Fireproof. Separated from strong bases and strong oxidants.
Spillage Disposal
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Eye Prevention
Wear safety goggles, face shield or eye protection in combination with breathing protection.
Fire Prevention
NO open flames, NO sparks and NO smoking. Above 61 °C use a closed system, ventilation and explosion-proof electrical equipment.
Inhalation Risk
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
Skin Prevention
Protective gloves. Protective clothing.
Ingestion Prevention
Do not eat, drink, or smoke during work.
Inhalation Prevention
Use ventilation, local exhaust or breathing protection.
Threshold Limit Values (TLV)
0.01 ppm as TWA; A4 (not classifiable as a human carcinogen).
Effects of Short Term Exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in lowering of consciousness.
TOXICITY
毒理信息
Adverse Effects
Neurotoxin - Acute solvent syndrome
Exposure Routes
The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion.
Signs and Symptoms
Confusion. Cough. Drowsiness. Dizziness. Shortness of breath. Sore throat. Unconsciousness.
Redness. Pain.
Redness. Pain.
Abdominal pain. Confusion. Dizziness. Drowsiness. Unconsciousness.
Toxicity Data
LC50 (rat) = 65,000 mg/m3/30min
REGULATORY
法规信息
Regulatory Information
Chemical: Ethane, iodo-
Ethane, iodo- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethane, iodo- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 27-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/24183
Iodoethane: Does not have an individual approval but may be used under an appropriate group standard
PHARMACOLOGY
药理信息
Metabolism/Metabolites
1-iodoethane has known human metabolites that include ethylglutathione.
USES
用途与制造
Uses
Has been used for the determination of cardiac output; [REPROTOX]
U.S. Production
2023: 31,870 lb;2022: 57,239 lb;2021: 54,564 lb;2020: 55,208 lb
Industry Uses
Catalyst
General Manufacturing Information
Plastics Material and Resin Manufacturing
Ethane, iodo-: ACTIVE
ALIASES
名称与别名
REACTIONS
参与反应
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