5-Hydroxypropafenone

HCID 107927CAS 86384-10-3
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
CCCNCC(O)COc1ccc(O)cc1C(=O)CCc1ccccc1
InChIKey
LUTWDNUXHDYZRA-UHFFFAOYSA-N
Summenformel
C21H27NO4
Durchschnittliche Molmasse
357,4 g/mol
Monoisotopische Masse
357,19400834

Überblick

5-hydroxypropafenone is a member of phenols.

Namen und Bezeichner

Bevorzugter Name
5-Hydroxypropafenone
IUPAC
1-[5-hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one
Englischer Name
5-Hydroxy propafenone hydrochloride
Summenformel
C21H27NO4
Molmasse
357.44

Namen und Synonyme

5-Hydroxypropafenone86384-10-3GPV-1297AC8BF38NP1-Propanone, 1-(5-hydroxy-2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-RefChem:9134635-HYDROXY PROPAFENONECHEMBL12641-[5-hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one1-{5-HYDROXY-2-[2-HYDROXY-3-(PROPYLAMINO)PROPOXY]PHENYL}-3-PHENYLPROPAN-1-ONELu 40-545 D5UNII-7AC8BF38NP
Weitere Namen anzeigen
Propafenone Impurity 425-Hydroxy Propefenone Hydrochloride5-Hydroxy propafenone hydrochloride5'-Hydroxy-2'-[2-hydroxy-3-(propylamino)propoxy]-β-phenylpropiophenone2'-[2-Hydroxy-3-(propylamino)propoxy]-5'-hydroxy-ω-phenylpropiophenone1-[5-Hydroxy-2-[2-hydroxy-3-(propylamino)propoxy]phenl]-3-phenyl-1-propanone,GPV129
1-(5-hydroxy-2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one1-(5-Hydroxy-2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanoneSCHEMBL2739132GPV 129CHEBI:171897DTXSID701006775BDBM50134995AKOS000277050

Datenbank-Bezeichner

CAS
86384-10-3
PubChem CID
107927
DTXSID
DTXSID701006775
ChEMBL
CHEMBL1264
ChEBI
CHEBI:171897
UNII
7AC8BF38NP
Nikkaji
J258.552I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
3
Polarare Oberfläche (TPSA)
78,8 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
5
Frei drehbare Bindungen
11
Schwere Atome
26

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Metabolite of Propafenone

Physikochemische Eigenschaften

Schmelzpunkt
210 · 210-216°C
Siedepunkt
564.4 · 564.4±50.0 °C(Predicted)
Dichte
1.153 · 1.153±0.06 g/cm3(Predicted)
storage temp.
-20 °C · -20°C Freezer
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid

Chemie und Industrie

Pharmakologische Informationen

Metabolism/Metabolites5-Hydroxypropafenone is a known human metabolite of Propafenone.
MeSH Pharmacological Classification · 2 Einträge

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Tissue LocationsKidney
Cellular LocationsCytoplasm

Anwendungen

VerwendenA metabolite of Propafenone (P757500).

Anbieter13 Anbieter

安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
玺标（上海）科技有限公司18512111473 18512111473 · [email protected]
Cato Research Chemicals Inc.020-81960175 · [email protected]
HBCChem, Inc.+1-510-219-6317 · [email protected]

Zugehörige Reaktionen

0
Reaktionsaufzeichnung erstellen

Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.

Verknüpfte Notizen

Wird geladen…