4-((2,2-Diphenylacetyl)oxy)-1,1-dimethylpiperidinium

HCID 1734CAS 81405-11-0
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Grundinformationen

Standard-SMILES
C[N+]1(C)CCC(OC(=O)C(c2ccccc2)c2ccccc2)CC1
InChIKey
HYJRTXSYDAFGJK-UHFFFAOYSA-N
Summenformel
C21H26NO2+
Durchschnittliche Molmasse
324,4 g/mol
Monoisotopische Masse
324,19580549

Überblick

4-DAMP(1+) is a quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine. It has a role as a cholinergic antagonist and a muscarinic antagonist.

Namen und Bezeichner

Bevorzugter Name
4-((2,2-Diphenylacetyl)oxy)-1,1-dimethylpiperidinium
IUPAC
(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetate
Englischer Name
4-diphenylacetoxy-1,1-dimethylpiperidinium
Summenformel
C21H26NO2
Molmasse
0

Namen und Synonyme

4-Diphenylacetoxy-1,1-dimethylpiperidinium81405-11-04-DAMP cationT2C393VHB9DTXSID702310861-dimethyl-4-diphenylacetoxypiperidinium4-((2,2-DIPHENYLACETYL)OXY)-1,1-DIMETHYLPIPERIDINIUMRefChem:911959DTXCID70153577[3H]4-DAMPCHEMBL168067106458-69-9
Weitere Namen anzeigen
4-DAMP(1+)4-Damp methobromide4-(Diphenylacetoxy)-1,1-dimethylpiperidin-1-ium1,1-Dimethyl-4-(diphenylacetoxy)piperidin-1-iumDiphenylacetic acid 1,1-dimethylpiperidinium-4-yl ester
CHEMBL768972-p-cyanophenyl-1,3-dithiolane(1,1-dimethylpiperidin-1-ium-4-yl) 2,2-diphenylacetateTocris-0482Lopac-D-104UNII-T2C393VHB9Lopac0_000407GTPL307

Datenbank-Bezeichner

CAS
81405-11-0
PubChem CID
1734
DTXSID
DTXSID70231086
ChEMBL
CHEMBL168067
ChEBI
CHEBI:73467
UNII
T2C393VHB9
Nikkaji
J257.583C

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4
Polarare Oberfläche (TPSA)
26,3 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
5
Schwere Atome
24

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.

Ergänzende Hinweise

DefinitionChEBI: A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.

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