Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine

HCID 23692652CAS 90693-88-2
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Grundinformationen

Standard-SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OC[C@H](N)C(=O)O)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Na+]
InChIKey
RRLDZFIFYLDDLI-OLZOWLLTNA-N
Summenformel
C42H77NNaO10P
Durchschnittliche Molmasse
810 g/mol

Namen und Bezeichner

Bevorzugter Name
Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine
IUPAC
sodium [(2S)-2-amino-2-carboxyethyl] [(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl] phosphate
Englischer Name
1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
Summenformel
C42H79NNaO10P
Molmasse
812.05

Namen und Synonyme

90693-88-2Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serineZBE12XT39T1,2-Dioleoyl-sn-glycero-3-phospho-serine, sodium salt1,2-Dioleoyl-sn-glycero-3-phospho-L-serine, sodium salt1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt)4,6,10-Trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-(((9Z)-1-oxo-9-octadecenyl)oxy)-, 5-oxide, sodium salt (1:1), (2S,8R,19Z)-RefChem:10986231,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodiumUNII-ZBE12XT39T1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt)DOPS sodium
Weitere Namen anzeigen
18:1 PS (DOPS)DOPS (18:1 PS)1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)1,2-Dioctadecenoyl-sn-glycero-3-PhosphoserineDioyl phosphatidylserine (sodium salt) (DOPS-NA)1,2-Dioleoyl-sn-glycero-3-phosphoserine sodium salt (DOPS Na)sodium O-(((R)-2,3-bis(oleoyloxy)propoxy)oxidophosphoryl)-L-serinate18:1 PS (DOPS)1,2-di - (9Z-octadecanoyl) - sn-glycero-3-phosphoyl-L-serine sodium salt
MFCD00133436DOPS-Na1,2-DIOLEOYLPHOSPHATIDYLSERINE (SODIUM SALT)Q272952841,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE MONOSODIUM SALT (OOPS)orb1940339SCHEMBL309891291,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium salt

Datenbank-Bezeichner

CAS
90693-88-2
PubChem CID
23692652
UNII
ZBE12XT39T

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
175 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
11
Frei drehbare Bindungen
42
Schwere Atome
55

Physikochemische Eigenschaften

storage temp.
-20 °C · Store at -20°C
Löslichkeit
10 mg/ml · Chloroform: 10 mg/ml
Aggregatzustand
A crystalline solid
Farbe
Light yellow to orange
Wasserlöslichkeit
soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)
InChIKey
RRLDZFIFYLDDLI-OLZOWLLTNA-N

Sicherheit und Regulatorisches

Sicherheitsdaten

wgk
WGK 3
Speicherklasse
13 - Non Combustible Solids

Chemie und Industrie

Anwendungen · 2 Einträge

Beschreibung1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model. DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.

Verwenden1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) is a lipid being studied in the assembly and long-term stability of solid supported lipid bilayers from artificial and natural lipid mixtures.

Anbieter50 Anbieter

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
Shochem(Shanghai) Co.,Ltd86-21-50800795 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]

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