HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Amino-5-methylthiazole
Meloxicam EP Impurity B · 2,5-amth · NSC 523150 · AKOS BBS-00006638 · BUTTPARK 18\10-87 · Meloxicam usp RC B · 2-Amino-5-methylthia · LABOTEST-BB LT00080645
Identifikatoren & physikalische Daten
| CAS No. | 7305-71-7 |
|---|---|
| Summenformel | C4H6N2S |
| Durchschnittliche Molmasse | 114,17 g/mol |
| Monoisotopische Masse | 114,02516919 g/mol |
| SMILES | Cc1cnc(N)s1 |
| InChIKey | GUABFMPMKJGSBQ-UHFFFAOYSA-N |
| PubChem CID | 351770 |
| ChEMBL | CHEMBL502447 |
| EC No. | 423-800-5 |
| DTXSID | DTXSID10223329 |
Chemische & physikalische Eigenschaften
| XLogP | 1 |
|---|---|
| Polarare Oberfläche (TPSA) | 67,2 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 66,7 |
| Schmelzpunkt | 93-98 °C (lit.) |
| Siedepunkt | 232.5±9.0 °C(Predicted) |
| Dichte | 1.258±0.06 g/cm3(Predicted) |
| Dampfdruck | 0.153-1.24Pa at 20-40℃ |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | soluble in Methanol |
| pKa (Säurekonstante) | 5.42±0.10(Predicted) |
| Aggregatzustand | Powder |
| Farbe | Brown |
| BRN | 109603 |
| InChI | 1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6) |
| InChIKey | GUABFMPMKJGSBQ-UHFFFAOYSA-N |
| SMILES | Cc1cnc(N)s1 |
| LogP (Verteilungskoeffizient) | 1.61 at 38℃ |
| Oberflächenspannung | 72.6mN/m at 1.02g/L and 20℃ |
| CAS Datenbank | 7305-71-7(CAS DataBase Reference) |
| NIST chemische Informationen | Thiazole, 2-amino-5-methyl-(7305-71-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302: Harmful if swallowed [Warning Acute toxicity, oral]P260, P264, P270, P273, P301+P317, P319, P330, P391, and P501 (click each P-code to see the statement)H302 (96.4%): Harmful if swallowed [Warning Acute toxicity, oral] |
|---|---|
| Regulatorische Informationen | Status: Active Update: 17-10-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/25186 |
| Hazard Classes and Categories | Acute Tox. 4 (96.4%)Acute Tox. 4 (100%)Acute toxicity - category 4Acute Tox. 4 * |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | 2811 |
| Zollcode | 29341000 |
| R-Sätze (R) | 22-48/22-50/53-36/37/38 |
| Gefahrensymbole | Xn,N,Xi |
| hazard_note | Irritant/Keep Cold |
| Sicherheitshinweise (S) | 60-61-29-26-37/39 |
| Gefahrenklasse | 9Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1STOT RE 2 |
| Verpackungsgruppe | III |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
An aminothiazole derivative used in characterization and DNA-interaction studies via formation of metal complexes that bind competitively to DNA. 2-Amino-5-methylthiazole can be used in solar cells to influence the interaction with the TiO2 photoelectrode, which in turn alters the dye-sensitized solar cell performance.