HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Hydroxy-2'-deoxycytidine
5-Oh-dc · 5-Ohdc · Aids088694 · Aids-088694 · 5-Hydroxydeoxycytidine · 5-Hydroxydeoxycytidine' · 2’-deoxy-5-hydroxycytidine · 2’-deoxy-5-hydroxy-cytidin
Identifikatoren & physikalische Daten
| CAS No. | 52278-77-0 |
|---|---|
| Summenformel | C9H13N3O5 |
| Durchschnittliche Molmasse | 243,22 g/mol |
| Monoisotopische Masse | 243,08552052 g/mol |
| SMILES | Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1O |
| InChIKey | CKZJTNZSBMVFSU-UBKIQSJTSA-N |
| PubChem CID | 477413 |
| ChEMBL | CHEMBL217849 |
| DTXSID | DTXSID00966652 |
Chemische & physikalische Eigenschaften
| XLogP | -1,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 129 |
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 17 |
| Formalladung | 0 |
| Komplexität | 394 |
| Schmelzpunkt | 109-110°C |
| Lagerbedingungen | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Löslichkeit | Methanol (Slightly), Water (Slightly) |
| Aggregatzustand | Solid |
| Farbe | White to Off-White |
| Stabilität | Hygroscopic |
Anwendungen & Verwendung
Verwenden
5-Hydroxy-2’-deoxycytidine have been used as a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNA due to exposure to reactive oxygen species.