HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
alpha-ethyl-2-oxo-1-Pyrrolidineacetamide
UCB-6474 · ETIRACETAM · rac-Levetiracetam · Etiracetam USP/EP/BP · SALOR-INT L127760-1EA · Levetiracetam Racemate · (+-)-1-pyrrolidineacetamid · Levetiracetam Impurity CRS
Identifikatoren & physikalische Daten
| CAS No. | 33996-58-6 |
|---|---|
| Summenformel | C8H14N2O2 |
| Durchschnittliche Molmasse | 170,21 g/mol |
| Monoisotopische Masse | 170,10552769 g/mol |
| SMILES | CCC(C(N)=O)N1CCCC1=O |
| InChIKey | HPHUVLMMVZITSG-UHFFFAOYSA-N |
| PubChem CID | 59708 |
| ChEMBL | CHEMBL1400561 |
| ChEBI | CHEBI:176724 |
| EC No. | 642-997-0 |
| DTXSID | DTXSID5046510 |
Chemische & physikalische Eigenschaften
| XLogP | -0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 63,4 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 203 |
| Schmelzpunkt | 113-114 °C(Solv: acetone (67-64-1)) |
| Siedepunkt | 395.9±25.0 °C(Predicted) |
| Dichte | 1.168±0.06 g/cm3(Predicted) |
| Dampfdruck | 0Pa at 25℃ |
| Lagerbedingungen | Store at -20°C |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly)401g/L at 20℃ |
| pKa (Säurekonstante) | 15.74±0.50(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to off-white |
| BRN | 1529106 |
| LogP (Verteilungskoeffizient) | 0.7 at 20℃ |
Sicherheit & Vorschriften
| UN-Transportnummer | UN 3077 9 / PGIII |
|---|---|
| Zollcode | 2933790002 |
| R-Sätze (R) | 22-36-51/53 |
| Toxizität | mouse,LD50,intravenous,1790mg/kg (1790mg/kg),United States Patent Document. Vol. #4696943, |
| Gefahrensymbole | Xn,N |
| Sicherheitshinweise (S) | 26-61 |
Anwendungen & Verwendung
Verwenden
A nootropic drug that produced a significant increase in β-wave activity and stimulated α-wave activity dose-dependently. Etiracetam has been used in studies to alleviate the effects of memory retrieval defic its in rats.