Hydrochloric Acid → HCID 178427847, Verbindung

Beteiligte Stoffe

Reaktionsschritte

Coupling of ketone 5 and 3-(4-fluoro-2-methylphenyl)-1-propylamine, using the method given in Example 1, gave 6-(trans-4-[3-(4-fluoro-2-methylphenyl)propylamino]cyclohexyl}-3H-benzoxazol-2-one (630 mg, 56%) as the HCl salt: 1H NMR (500 MHz, DMSO-d6): δ 11.50 (s, 1H), 8.88 (s, 2H), 7.22-7.13 (m, 2H), 7.05-6.91 (m, 4H), 3.09-2.87 (m, 3H), 2.67-2.62 (m, 3H), 2.30 (s, 3H), 2.17-2.13 (m, 2H), 1.92-1.79 (m, 4H), 1.58-1.41 (m, 4H).

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