HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen Bromide → 2-Bromo-1-oxoindan-5-carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen Bromide | HCID 260 | — |
| Edukt | Bromine | HCID 24408 | — |
| Edukt | 1-oxo-2,3-dihydro-1H-indene-5-carbonitrile | HCID 312896 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 2-Bromo-1-oxoindan-5-carbonitrile | HCID 18407238 | — |
Reaktionsschritte
1-Oxoindane-5-carbonitrile is brominated with bromine in glacial acetic acid with addition of a catalytic amount of 48% strength HBr solution in water and affords 2-bromo-1-oxoindane-5-carbonitrile with a melting point of 115-118° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06476059B1 |
| Quelldatensatz | uspto-grants-2002_11 |
| ORD ID | ord-6e54ad14693d46c5a0dc92736c8e474b |
| Quellennotiz | uspto-grants-2002_11 |