HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Boronic acid, (4-ethylphenyl)- → 5-(4-Ethylphenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Boronic acid, (4-ethylphenyl)- | HCID 2734352 | — |
| Edukt | 5-Bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid | HCID 58192592 | — |
| Produkt | 5-(4-Ethylphenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 66678486 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example BQ using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1211586-75-2) and B-(4-ethylphenyl)-boronic acid, (CAN 63139-21-9) as starting materials; LC-MS (UV peak area/ESI) 95.8%, 324.0859 (M−H)−.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08729105B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-c8e2f92284ad4f2e8a619e57b49bec6b |
| Quellennotiz | uspto-grants-2014_05 |