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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1038005Erstellt: 23. Oktober 2026

N-methyl-5-nitro-1H-indazole-3-carboxamide → 5-Amino-N-methyl-1H-indazole-3-carboxamide

https://huagongshe.com/de/reaction/1038005

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktN-methyl-5-nitro-1H-indazole-3-carboxamideHCID 45810073—
KatalysatorPalladiumHCID 23938—
LösungsmittelMethanolHCID 887—
Produkt5-Amino-N-methyl-1H-indazole-3-carboxamideHCID 22567319105,1%

Reaktionsschritte

To a suspension of compound 55 (65 mg) in 5 mL of methanol was added catalytic amount of 5% palladium on carbon. The mixture was stirred under a hydrogen atmosphere at room temperature for 4 hrs and filtered through celite. The filtrate was concentrated to afford compound 56 (59 mg).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08546404B2
Quelldatensatzuspto-grants-2013_10
ORD IDord-7008f161220d40e19af52abfa231e6b5
Quellennotizuspto-grants-2013_10