HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-methyl-5-nitro-1H-indazole-3-carboxamide → 5-Amino-N-methyl-1H-indazole-3-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-methyl-5-nitro-1H-indazole-3-carboxamide | HCID 45810073 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 5-Amino-N-methyl-1H-indazole-3-carboxamide | HCID 22567319 | 105,1% |
Reaktionsschritte
To a suspension of compound 55 (65 mg) in 5 mL of methanol was added catalytic amount of 5% palladium on carbon. The mixture was stirred under a hydrogen atmosphere at room temperature for 4 hrs and filtered through celite. The filtrate was concentrated to afford compound 56 (59 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08546404B2 |
| Quelldatensatz | uspto-grants-2013_10 |
| ORD ID | ord-7008f161220d40e19af52abfa231e6b5 |
| Quellennotiz | uspto-grants-2013_10 |