HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(2-Bromoethoxy)tetrahydro-2H-pyran → 1-(2-Hydroxyethyl)-4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(2-Bromoethoxy)tetrahydro-2H-pyran | HCID 86621 | — |
| Edukt | 4-Methyl-N-(piperidin-4-YL)isoquinolin-5-amine hydrochloride | HCID 21979810 | — |
| Produkt | 1-(2-Hydroxyethyl)-4-(4-methyl-5-isoquinolyl)aminopiperidine hydrochloride | HCID 21979983 | — |
Reaktionsschritte
According to the method of Example 144, an alkylation reaction with 2-(2-bromoethoxy)tetrahydro-2H-pyran and a deprotection reaction were performed by using the compound of Example 106 to obtain the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07094789B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-d00bddfa7b8a4ef6b23783ff72234805 |
| Quellennotiz | uspto-grants-2006_08 |