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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 10817Erstellt: 24. Oktober 2026

Cyanamide → {4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-benzo[1,3]dioxol-5-yl-methanone

https://huagongshe.com/de/reaction/10817

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyanamideHCID 9864—
Edukt1-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-oneHCID 243777—
Edukt1-(4-Isothiocyanatophenyl)-4-cyclopropylmethylpiperazineHCID 21958916—
Produkt{4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-benzo[1,3]dioxol-5-yl-methanoneHCID 10277319—

Reaktionsschritte

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-[(benzo[1,3]dioxol-5-yl)ethanone (of Example 11) following the procedure used in Example 24 Mass spectrum (ES) MH+=478.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07094896B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-8d916d1a8d734bca8f579d63c504873f
Quellennotizuspto-grants-2006_08