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HRID 10845Erstellt: 24. Oktober 2026

3-Hydroxyphthalic anhydride → Methyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate

https://huagongshe.com/de/reaction/10845

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Hydroxyphthalic anhydrideHCID 96580—
EduktMethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982209—
ProduktMethyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982178—

Reaktionsschritte

Methyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.84 g, 45%) in the same manner as described in the above example 5 (1) from methyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (1.00 g, 5.54 mmol) and 3-hydroxyphthalic anhydride (1.00 g, 6.09 mmol), and the obtained product was identified with the following NMR data.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07094908B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-4d9bd298abef4d1a8592a82a173535b8
Quellennotizuspto-grants-2006_08