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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 10860Erstellt: 24. Oktober 2026

3-Hydroxyphthalic anhydride → Ethyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate

https://huagongshe.com/de/reaction/10860

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Hydroxyphthalic anhydrideHCID 96580—
EduktEthyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982228—
ProduktEthyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982235—

Reaktionsschritte

Ethyl 3-(4-hydroxy-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.46 g, 67%) in the same manner as described in the above example 5 (20) from ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.40 g, 1.96 mmol) and 3-hydroxyphthalic anhydride (0.42 g, 2.16 mmol), and the obtained product was identified with the following NMR data.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07094908B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-958756ffd18845888710f0970aeb4d2c
Quellennotizuspto-grants-2006_08