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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1108073Erstellt: 24. Oktober 2026

4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran → 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran

https://huagongshe.com/de/reaction/1108073

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyranHCID 11287160—
Edukt1-(4-Chloromethylphenyl)-2-methyl-1H-imidazoleHCID 14998821—
Produkt4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyranHCID 1134931138%

Reaktionsschritte

4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran was reacted with 4-(2-methylimidazol-1-yl)benzylchloride to give the titled compound in 38% yield as colorless needles according to the procedure described in Example 2H.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06063928
Quelldatensatzuspto-grants-2000_05
ORD IDord-4ba22721a4784675b2d3480b6f9d5e73
Quellennotizuspto-grants-2000_05