HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(4'-ethyl-3'-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid | HCID 5210422 | — |
| Edukt | 1-Ethyl-2-methylpiperazine | HCID 17750365 | — |
| Produkt | 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(4'-ethyl-3'-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid | HCID 10109876 | 51% |
Reaktionsschritte
The condensation of 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 4-ethyl-3-methylpiperazine was carried out in a similar manner as described in example 1 gave the titled product. Yield 51%, m.p 200° C., C20H24FN3O3, m/z 374 (M+1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07098219B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-f878f40338784547baf46f135f7a5b94 |
| Quellennotiz | uspto-grants-2006_08 |