HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethylamine → N'-[4-(1,2,2,6,6-Pentamethyl-piperidin-4-ylcarbamoyl)-phenyl]-hydrazinecarboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethylamine | HCID 6341 | — |
| Edukt | 4-Amino-1,2,2,6,6-pentamethylpiperidine | HCID 693792 | — |
| Edukt | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Edukt | 4-(2-(tert-Butoxycarbonyl)hydrazinyl)benzoic acid | HCID 2755984 | — |
| Lösungsmittel | Dimethylacetamide | HCID 31374 | — |
| Produkt | N'-[4-(1,2,2,6,6-Pentamethyl-piperidin-4-ylcarbamoyl)-phenyl]-hydrazinecarboxylic acid tert-butyl ester | HCID 59515583 | — |
Reaktionsschritte
To a solution of 4-(N′-tert-Butoxycarbonyl-hydrazino)-benzoic acid (4.452 g) in DMA (30 ml) was added disopropyl ethyl amine (6.16 ml) and HBTU (6.69 g) with stirring at room temp. 4-Amino-1,2,2,6,6-pentamethylpiperidine (3 g) was then added to the stirred solution. Stirring continued at room temp for 4 hrs.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07816361B2 |
| Quelldatensatz | uspto-grants-2010_10 |
| ORD ID | ord-bea97ea435f440fe82eb8e6b2adb9c14 |
| Quellennotiz | uspto-grants-2010_10 |