HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1160134Erstellt: 24. Oktober 2026
Ethanol → 4-(3-Isoxazol-5-yl-5-oxo-2,5-dihydro-pyrazol-1-yl)-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide
https://huagongshe.com/de/reaction/1160134
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | 4-Hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide | HCID 59515576 | — |
| Edukt | 3-Isoxazol-5-yl-3-oxo-propionic acid ethyl ester | HCID 59515581 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Produkt | 4-(3-Isoxazol-5-yl-5-oxo-2,5-dihydro-pyrazol-1-yl)-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide | HCID 59515579 | — |
Reaktionsschritte
3-Isoxazol-5-yl-3-oxo-propionic acid ethyl ester (49 mg) and 4-Hydrazino-N-(1,2, 2,6,6-pentamethyl-piperidin-4-yl)-benzamide (93 mg) were dissolved into ethanol (2.5 ml) and acetic acid (0.3 ml) and the solution stirred at 65° C. for 2 h. Concentration in vacuo and purification by HPLC gave the expected product. LC/MS: main peak is product (m/z: 424.3)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07816361B2 |
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| Quelldatensatz | uspto-grants-2010_10 |
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| ORD ID | ord-9b474b85717541bdb5e07a40b4590530 |
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| Quellennotiz | uspto-grants-2010_10 |
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