HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Anhydride → 1-Acetylindolin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Anhydride | HCID 7918 | — |
| Edukt | Oxindole | HCID 321710 | — |
| Produkt | 1-Acetylindolin-2-one | HCID 323719 | 93,7% |
Reaktionsschritte
Indoline-2-one (6.65 g, 50 mmol) and acetic anhydride (9 mL) were heated at reflux for 15 h. After cooling, the product was filtered and rinsed with Et2O to give 2a as solids after vacuum drying (8.2 g, yield: 93.7 %).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728008B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-a7734ec7f6ab472a91dc21117afbdc06 |
| Quellennotiz | uspto-grants-2010_06 |