HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Aminomethyl)-3-chlorobenzonitrile → (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Aminomethyl)-3-chlorobenzonitrile | HCID 4089788 | — |
| Edukt | (RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid | HCID 67373142 | — |
| Produkt | (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide | HCID 21904934 | — |
Reaktionsschritte
(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid, described in example 15.1 was coupled with 4-aminomethyl-3-chlorobenzonitrile (CAS 202521-97-9) according to general procedure B to give (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide. Light green solid. MS 361.1 ([M−H]−)
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07129238B2 |
| Quelldatensatz | uspto-grants-2006_10 |
| ORD ID | ord-14303f6a4416476f9f75ea88e88ce94f |
| Quellennotiz | uspto-grants-2006_10 |