HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(S)-Benzyl 2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate → (2S)-N,N-dimethylpyrrolidine-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (S)-Benzyl 2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate | HCID 13564352 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | HCID 178418390 | HCID 178418390 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | (2S)-N,N-dimethylpyrrolidine-2-carboxamide | HCID 7408249 | 99% |
Reaktionsschritte
In 86 ml of ethanol was dissolved 4.3 g of compound (88) and after adding thereto 210 mg of 10% palladium-carbon, the mixture was stirred vigorously for 90 minutes in a hydrogen stream, After filtering off the catalyst, ethanol was distilled off under reduced pressure to provide 2.19 g of crude (S)-N,N-dimethyl-2-pyrrolidinecarboxamide (89).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04564609 |
| Quelldatensatz | uspto-grants-1986_01 |
| ORD ID | ord-9f85be37924f41cbbf5059ae1c55f018 |
| Quellennotiz | uspto-grants-1986_01 |