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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1289477Erstellt: 24. Oktober 2026

Trimethylsilyl cyanide → 4-Bromo-2-cyanopyridine

https://huagongshe.com/de/reaction/1289477

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTrimethylsilyl cyanideHCID 82115—
Edukt4-Bromopyridin-1-ium-1-olateHCID 139708—
Produkt4-Bromo-2-cyanopyridineHCID 693283—

Reaktionsschritte

The title compound was prepared from 4-bromopyridine-1-oxide (Rec. Trav. chim., 1951, 70, 581) and trimethylsilyl cyanide, using the procedure described in Chem. Pharm. Bull., 1985, 33, 565, and obtained as a solid (49% yield), m.p. 88°-93° C. Rf 0.53 (SS 11). Found: C,39.15; H,1.50; N,15.07. C6H3BrN2 requires C,39.37; E,1.65; N,15.30%.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05750520
Quelldatensatzuspto-grants-1998_05
ORD IDord-b9e28d64c47c4e2bbcdbe54b64ba0176
Quellennotizuspto-grants-1998_05