Potassium Carbonate → 1-Benzyl-4-(4-nitrophenyl)-[1,4]diazepane

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Fluoronitrobenzene (3.09 g, 21.9 mmol) is dissolved in water (14 ml), and then potassium carbonate (3.64 g, 26.28 mmol) and 1-benzylhomopiperazine (5 g, 26.28 mmol) are added. The medium is heated at 90° C. for 4 h 20 min and then cooled to room temperature. The precipitate formed is filtered, and a yellow solid is obtained. 6.30 g (92.5%) of product are recovered.

Herkunft & Nachweise