HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Morpholine → (5-hydroxy-1H-indol-2-yl)-morpholin-4-yl-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Morpholine | HCID 8083 | — |
| Edukt | 5-Hydroxyindole-2-carboxylic acid | HCID 88958 | — |
| Edukt | [5-Hydroxy-1-(2,2,2-trifluoro-ethyl)-1H-indol-2-yl]-morpholin-4-yl-methanone | HCID 67527268 | — |
| Produkt | (5-hydroxy-1H-indol-2-yl)-morpholin-4-yl-methanone | HCID 44185244 | — |
Reaktionsschritte
In analogy to the procedure described for the synthesis of intermediate 1, step 4, the title compound was synthesized from 5-hydroxy-1H-indole-2-carboxylic acid (purchased at Fluka, Ref 55355) and morpholine. The desired product was obtained in 86% yield as white solid. MS (m/e): 493.1 (2M+, 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07388095B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-3d1545c0174344af888da1f2167d0abb |
| Quellennotiz | uspto-grants-2008_06 |