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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 13314Erstellt: 24. Oktober 2026

1-methyl-1H-pyrazole-3-carboxylic acid → 5-(2,4-Difluoro-phenoxy)-2-(1-methyl-1H-pyrazol-3-yl)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole

https://huagongshe.com/de/reaction/13314

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-methyl-1H-pyrazole-3-carboxylic acidHCID 573176—
Edukt5-(2,4-Difluoro-phenoxy)-2-pyridin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazoleHCID 23145249—
Produkt5-(2,4-Difluoro-phenoxy)-2-(1-methyl-1H-pyrazol-3-yl)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazoleHCID 135697988—

Reaktionsschritte

The entitled compound was obtained as a colorless solid in the same method as in Example 203 or in accordance with the method or by combining it with an ordinary method but using 4-(2,4-difluoro-phenoxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 229 and 1-methyl-1H-pyrazole-3-carboxylic acid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07728025B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-b35ce76bb3254f7e9b6704664e3eedb4
Quellennotizuspto-grants-2010_06