HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dabco → 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dabco | HCID 9237 | — |
| Edukt | 1-[4-(4-Bromomethylbenzyloxy)-phenyl]-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-(4-methoxyphenyl)-azetidin-2-one | HCID 21083167 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide | HCID 21083163 | — |
Reaktionsschritte
Compound (25) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (26) as a colorless solid of molecular weight 716.70 (C39H43BrFN3O4); MS (ESI): 636.3 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07390790B2 |
| Quelldatensatz | uspto-grants-2008_06 |
| ORD ID | ord-b3bfa02d929d4a65bd51a30abd576fce |
| Quellennotiz | uspto-grants-2008_06 |