HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(4-Methylpiperazine-1-carbonyl)phenylboronic acid → 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(4-(4-methylpiperazine-1-carbonyl)phenyl)isoquinolin-3-yl)cyclopropanecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(4-Methylpiperazine-1-carbonyl)phenylboronic acid | HCID 12993042 | — |
| Edukt | N-(1-Bromoisoquinolin-3-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide | HCID 57732996 | — |
| Edukt | 2,2-difluorobenzo[d][1,3]dioxol-5-yl-N-(1-phenylisoquinolin-3-yl)cyclopropanecarboxamide | HCID 57733001 | — |
| Produkt | 1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(4-(4-methylpiperazine-1-carbonyl)phenyl)isoquinolin-3-yl)cyclopropanecarboxamide | HCID 57733022 | — |
Reaktionsschritte
1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-phenylisoquinolin-3-yl)cyclopropanecarboxamide was made by the procedure shown above starting from N-(1-bromoisoquinolin-3-yl)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamide and 4-(4-methylpiperazine-1-carbonyl)phenylboronic acid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09012473B2 |
| Quelldatensatz | uspto-grants-2015_04 |
| ORD ID | ord-0dbff496d83d4363b4bfae3833bc212c |
| Quellennotiz | uspto-grants-2015_04 |