Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Thiophenol | HCID 7969 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 1-Propanone, 2-chloro-2-methyl-1-phenyl- | HCID 81985 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-Propanone, 2-methyl-1-phenyl-2-(phenylthio)- | HCID 12270589 | — |
Reaktionsschritte
10.88 g of a 50% suspension of sodium hydride in paraffin mineral oil are fed into 100 ml of DMF, followed slowly by 25.11 g of thiophenol. When dissolution is complete (65° C.), the solution is cooled to 2° C. and 36.5 g of 2-chloro-2-methylpropiophenone are fed in over 30 minutes maintaining the temperature below 10° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US05026740 |
|---|
| Quelldatensatz | uspto-grants-1991_06 |
|---|
| ORD ID | ord-5752ad7ba6814d479c4aac8bf2293d7c |
|---|
| Quellennotiz | uspto-grants-1991_06 |
|---|
