HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Propane, 1-chloro-3-isocyanato- → 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)tetrahydro-2(1H)-pyrimidinone dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Propane, 1-chloro-3-isocyanato- | HCID 166752 | — |
| Edukt | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| Produkt | 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)tetrahydro-2(1H)-pyrimidinone dihydrochloride | HCID 49851165 | 87% |
Reaktionsschritte
The title compound was prepared in 87% yield according to the general procedure for the synthesis of cyclic ureas and carbamates (Method G) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D3) and 1-chloro-3-isocyanatopropane.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732600B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-c3dfc8e46f1f45baace105d247254803 |
| Quellennotiz | uspto-grants-2010_06 |