Sodium Acetate → 1-(2-Aminothiazol-4-yl)-1-propencarboxylic acid ethyl ester

Beteiligte Stoffe

Reaktionsschritte

to a solution of 190 g of the product of example 81 in 400 ml tetrahydrofuran were added first a solution of 82 g sodium acetate in 150 ml of water and then 76 g thiourea. The solution was stirred at room temperature for 20 hours, then the THF was distilled off and acetic acid ethyl ester was added to the residue.

Herkunft & Nachweise