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HRID 16559Erstellt: 24. Oktober 2026

1,2-Diamino-3,5-bis(trifluoromethyl)benzene → N-[5,7-Bis(trifluoromethyl)benzimidazol-2-yl]-1,2,3,4-tetrahydro-1-naphthylamine

https://huagongshe.com/de/reaction/16559

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1,2-Diamino-3,5-bis(trifluoromethyl)benzeneHCID 2773214—
Edukt1-Isothiocyanato-1,2,3,4-tetrahydronaphthaleneHCID 21393478—
ProduktN-[5,7-Bis(trifluoromethyl)benzimidazol-2-yl]-1,2,3,4-tetrahydro-1-naphthylamineHCID 11603683—

Reaktionsschritte

The title compound was prepared from 3,5-bis(trifluoromethyl)-1,2-diaminobenzene and 1-isothiocyanato-1,2,3,4-tetrahydronaphthalene by Procedure D. The title compound was isolated by column chromatography as the free base and as a mixture of enantiomers (solid, dec. >240° C.). MS(ES+) m/z 400 ([M+1]+, 100).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07737167B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-eed1159a40e24904984eac4e15d275ed
Quellennotizuspto-grants-2010_06