HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Iodo-2-(trifluoromethyl)pyridine → (S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Iodo-2-(trifluoromethyl)pyridine | HCID 23436940 | — |
| Edukt | (R)-methyl2-(tert-butoxycarbonyl)-3-iodopropanoate | HCID 86614124 | — |
| Produkt | (S)-Methyl2-(tert-butoxycarbonyl)-3-(2-(trifluoromethyl)pyridin-4-yl)propanoate | HCID 67165305 | — |
Reaktionsschritte
The title compound was prepared according to previously reported procedure (see pending U.S. patent application Ser. No. 11/575,187) from (R)-methyl 2-(tert-butoxycarbonyl)-3-iodopropanoate and 4-iodo-2-(trifluoromethyl)pyridine (this starting material was prepared according to a procedure described in Eur. J. Org. Chem. 2003, 1559-1568).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08163909B2 |
| Quelldatensatz | uspto-grants-2012_04 |
| ORD ID | ord-cbebf66771c04952bc7e7dd7c5332e4f |
| Quellennotiz | uspto-grants-2012_04 |