HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenelzine → (2S,4R)-4-Cyclopropylmethanesulfonyl-1-(5-methyl-2-phenethyl-2H-pyrazol-3-yl)-pyrrolidine-2-carboxylic Acid Methyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenelzine | HCID 3675 | — |
| Edukt | (2S,4R)-4-Cyclopropylmethanesulfonyl-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic Acid Methyl Ester | HCID 86646864 | — |
| Produkt | (2S,4R)-4-Cyclopropylmethanesulfonyl-1-(5-methyl-2-phenethyl-2H-pyrazol-3-yl)-pyrrolidine-2-carboxylic Acid Methyl Ester | HCID 67278218 | — |
Reaktionsschritte
In analogy to the procedure described in example 192 h, (2S,4R)-4-cyclopropylmethanesulfonyl-1-(3-oxo-thiobutyryl)-pyrrolidine-2-carboxylic acid methyl ester (example 445c) was reacted with 1-(2-phenylethyl)hydrazine (CAS Reg. No. 51-71-8) to give the title compound as brown solid. MS (ESI): m/z=432.6 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08163793B2 |
| Quelldatensatz | uspto-grants-2012_04 |
| ORD ID | ord-dd1d37cdf4f343aab6f505ebcd8fe6e7 |
| Quellennotiz | uspto-grants-2012_04 |