HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethylamine → Propacetamol hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethylamine | HCID 8021 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 4-Acetamidophenyl chloroacetate | HCID 13277664 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | Propacetamol hydrochloride | HCID 108082 | 39,8% |
Reaktionsschritte
22.8 g of p-acetamidophenyl chloroacetate were added in small portions to a solution of 7.5 g of diethylamine in 30 c.c. of triethylamine with stirring, while the temperature was maintained at between 40° C. and 50° C. with a bath of cold water if necessary. The process described in Example 1 was then followed to obtain 12 g of p-acetamidophenyl diethylaminoacetate hydrochloride melting point = 228° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04127671 |
| Quelldatensatz | uspto-grants-1978_11 |
| ORD ID | ord-abc1d9f1c5e84e8e9fbe8e110565d271 |
| Quellennotiz | uspto-grants-1978_11 |