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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1704741Erstellt: 24. Oktober 2026

Diethylamine → Propacetamol hydrochloride

https://huagongshe.com/de/reaction/1704741

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDiethylamineHCID 8021—
EduktTriethylamineHCID 8471—
Edukt4-Acetamidophenyl chloroacetateHCID 13277664—
LösungsmittelWaterHCID 962—
ProduktPropacetamol hydrochlorideHCID 10808239,8%

Reaktionsschritte

22.8 g of p-acetamidophenyl chloroacetate were added in small portions to a solution of 7.5 g of diethylamine in 30 c.c. of triethylamine with stirring, while the temperature was maintained at between 40° C. and 50° C. with a bath of cold water if necessary. The process described in Example 1 was then followed to obtain 12 g of p-acetamidophenyl diethylaminoacetate hydrochloride melting point = 228° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04127671
Quelldatensatzuspto-grants-1978_11
ORD IDord-abc1d9f1c5e84e8e9fbe8e110565d271
Quellennotizuspto-grants-1978_11