HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Acetylbutyric acid → 1-(3'-Amino-4',6'-dimethylphenyl)-6-methyl-piperidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Acetylbutyric acid | HCID 18407 | — |
| Edukt | 4,6-Diamino-1,3-m-xylene | HCID 854386 | — |
| Katalysator | Nickel | HCID 935 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 1-(3'-Amino-4',6'-dimethylphenyl)-6-methyl-piperidin-2-one | HCID 20494961 | — |
Reaktionsschritte
A solution of 65 g (0.5 mol) of 5-oxo-caproic acid and 70 g (0.51 mol) of 3-amino-4,6-dimethylaniline in 300 ml of methanol is hydrogenated at 130°-140° in the presence of Raney nickel. Yield: 110 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04208202 |
| Quelldatensatz | uspto-grants-1980_06 |
| ORD ID | ord-df65ea40835d42188f9f9137dcd712c8 |
| Quellennotiz | uspto-grants-1980_06 |