HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pamoic Acid → Octreotide pamoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pamoic Acid | HCID 8546 | — |
| Edukt | Octreotide | HCID 448601 | — |
| Lösungsmittel | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Produkt | Octreotide pamoate | HCID 44194024 | — |
Reaktionsschritte
10.19 g of octreotide free base (10 mM) and 3.88 embonic acid (10 mM) are dissolved in 1 liter of water/dioxane (1:1). The reaction mixture is filtered, and lyophilized to give a yellow powder [α]20D=+7.5° (C=0.35, in DMF), of octreotide pamoate hydrate. Factor=1.4 wherein the factor=weight of lyophilizate/weight of octreotide contained therein.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05538739 |
| Quelldatensatz | uspto-grants-1996_07 |
| ORD ID | ord-b47e8b278e13464894097467ad20f6c6 |
| Quellennotiz | uspto-grants-1996_07 |