Isocaproaldehyde → (5R)-5-ethyl-9-fluoro-5-hydroxy-12-isopentyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Isocaproaldehyde	HCID 129	—
Edukt	(5R)-5-ethyl-9-fluoro-5-hydroxy-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione	HCID 9929755	—
Produkt	(5R)-5-ethyl-9-fluoro-5-hydroxy-12-isopentyl-4,5,13,15-tetrahydro-1H,3H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione	HCID 69591048	—

The product of Example 2 is treated with 4-methylpentanal according to a procedure similar to Stage 13e in order to produce the expected solid.