HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione → (RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Edukt | 4-(4-Trifluoromethyl-benzyloxy)-phenylamine | HCID 22137889 | — |
| Produkt | (RS)-2-oxo-1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid | HCID 23614753 | — |
Reaktionsschritte
The title compound is prepared in analogy to Example 3c) from 4-(4-trifluoromethyl-benzyloxy)-phenylamine and 6,6-dimethyl-5,7-dioxa-spiro[2,5]octane-4,8-dione. Yield: 37% of a colorless solid. MS: m/e=380.1 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07235581B2 |
| Quelldatensatz | uspto-grants-2007_06 |
| ORD ID | ord-e82aceb8b5e7496b8dca613177d52431 |
| Quellennotiz | uspto-grants-2007_06 |