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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1795433Erstellt: 24. Oktober 2026

Ethanol, 1-ethoxy-2,2,2-trifluoro- → 4-Trifluoromethyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

https://huagongshe.com/de/reaction/1795433

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEthanol, 1-ethoxy-2,2,2-trifluoro-HCID 9897—
Edukt4-Trifluoromethyl-7-methyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 10270119—
Produkt4-Trifluoromethyl-6-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 10154869—

Reaktionsschritte

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1=H, n=1) and trifluoroacetaldehyde ethyl hemiacetal. 1H NMR (400 MHz, CDCl3) 11.32 (br. s, 1H), 7.11 (s, 1H), 7.02 (s, 1H), 6.99 (s, 1H), 3.88 (q, 2H, J=8.9), 3.47 (t, 2H, J=5.6), 2.93 (t, 2H, J=6.3), 2.03 (m, 2H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07026484B2
Quelldatensatzuspto-grants-2006_04
ORD IDord-51646d06e7ac417ab0c42bc6c479963e
Quellennotizuspto-grants-2006_04